Thursday, February 21, 2008

Lasers that put voices in your head

Via Physorg.com:

A recently unclassified report from the Pentagon from 1998 has revealed an investigation into using laser beams for a few intriguing potential methods of non-lethal torture. Some of the applications the report investigated include putting voices in people's heads, using lasers to trigger uncontrolled neuron firing, and slowly heating the human body to a point of feverish confusion - all from hundreds of meters away.

A US citizen requested access to the document, entitled "Bioeffects of Selected Non-Lethal Weapons," under the Freedom of Information Act a little over a year ago. There is no evidence that any of the technologies mentioned in the 10-year-old report have been developed since the time it was written.

The report explained several types of non-lethal laser applications, including microwave hearing, disrupted neural control, and microwave heating. For the first type, short pulses of RF energy (2450 MHz) can generate a pressure wave in solids and liquids. When exposed to pulsed RF energy, humans experience the immediate sensation of "microwave hearing" - sounds that may include buzzing, ticking, hissing, or knocking that originate within the head.

Studies with guinea pigs and cats suggest that the mechanism responsible for the phenomenon is thermoelastic expansion. Exposure to the RF pulses doesn´t cause any permanent effects, as all effects cease almost immediately after exposure ceases. As the report explains, tuning microwave hearing could enable communicating with individuals from a distance of up to several hundred meters.

"The phenomenon is tunable in that the characteristic sounds and intensities of those sounds depend on the characteristics of the RF energy as delivered," the report explains. "Because the frequency of the sound heard is dependent on the pulse characteristics of the RF energy, it seems possible that this technology could be developed to the point where words could be transmitted to be heard like the spoken word, except that it could only be heard within a person´s head. In one experiment, communication of the words from one to ten using ´speech modulated´ microwave energy was successfully demonstrated. Microphones next to the person experiencing the voice could not pick up these sounds. Additional development of this would open up a wide range of possibilities."

The report predicts that communicating at longer distances would be possible with larger equipment, while shorter range signals could be generated with portable equipment. Putting voices in people´s heads could cause what the report calls "psychologically devastating" effects. The technology might even allow for communicating with an individual hostage surrounded by captors, although this would require "extreme directional specificity."

With another weapon, electromagnetic pulses could be used to disrupt the brain´s functioning, although this technology was still in the theoretical stages at the time.

Under normal conditions, all brain structures function with specific rhythmic activity depending on incoming sensory information. Sometimes, the brain synchronizes neuronal activity in order to focus on a specific task, but the degree of neuronal synchronization is highly controlled. However, under certain conditions (such as physical stress or heat stroke), more areas of the brain can fire in a highly synchronized manner, and may begin firing uncontrollably.

The report describes a method for replicating this highly synchronized neuron firing across distances of several hundred meters. High-voltage (100 kV/m) electromagnetic pulses lasting for one nanosecond could trigger neurons to fire, disrupting the body´s controlled firing activity. Short-term effects may include loss of consciousness, muscle spasms, muscle weakness, and seizures lasting for a couple minutes. These high-voltage pulsed sources, which would require an estimated frequency of 15 Hz, exist today.

Another form of non-lethal torture described in the report is microwave heating. By raising the temperature of the body to 41°C (105.8°F), humans can experience sensations such as memory loss and disorientation, and exhibit reduced aggression. According to the report, humans can survive temperatures up to 42°C (107.6°F), at which time prolonged exposure can result in permanent brain damage or death.

The microwave heating technique was tested on a Rhesus monkey, where a 225 MHz beam caused an increase in the animal´s body temperature. Depending on the dosage level, the temperature increase occurred within a time of 15 to 30 minutes. After the beam was removed, the animal´s body temperature decreased back to normal. The report suggests the technique could be useful for controlling crowds or in negotiations.

While the investigations reveal intriguing techniques for non-lethal torture, the report does not mention plans for carrying out specific experiments or studies in the future.

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Saturday, January 26, 2008

Transplant eyeball sent to pub

From the Courier Mail:

David Killick

January 24, 2008 07:21am

AN EYEBALL sent from Queensland for a transplant operation in Hobart went astray this week - arriving at a pub instead of the hospital.

A hotel guest in the Tasmanian city of Hobart was shocked when he received a foam box on Tuesday night containing a single human eyeball.

The box marked ``Live human organs for transplant'' was delivered by mistake by an unwitting taxi driver.

Hotel worker Gabriel Winner - who requested the name of the hotel not be used - says the agitated guest brought the esky to reception early yesterday morning.

``The guy left with me with a box with an eyeball in it,'' he said.

``He got the box and signed for it and opened it in the middle of the night.

``I thought this is just too weird. I went and put it in the fridge because I didn't know what else to do with it. It was more than a little disconcerting.''

A courier arrived shortly after and took the esky away.

Tracking records for the consignment number on the esky confirmed Australian Air Express picked the package up in Brisbane shortly before 4pm on Tuesday.

The package was dropped at 9.40pm that night. An Australian Air Express spokeswoman confirmed a ``failure in an internal handover process'' which meant the taxi driver was given the wrong package to deliver.

She said the company sincerely regretted the incident.

``As soon as we discovered the error we quickly rectified that and delivered the consignment within the appropriate timeframe,'' she said.

Mr Winner said he was disappointed that someone could have missed out on an operation because of such a basic error.

"It says on the box `human eye tissue for transplant'. What it probably means is the person who was relying on this piece of human tissue has now had to postpone their operation.

``Somebody died to donate these organs to somebody else and they've screwed it up and it's probably not even viable now.''

Queensland Health spokeswoman Penny Geraghty confirmed the incident but said tissue from the eye was recovered and successfully transferred to a patient yesterday morning.

``Nobody missed their operation. The tissue wasn't compromised,'' she said.

She said this was the first time an incident of this type had occurred.

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Friday, January 25, 2008

Teen changes blood group, immune system

From the Toronto Star:

Jan 25, 2008 12:42 PM
Reuters

CANBERRA - An Australian teenage girl has become the world's first known transplant patient to change blood groups and take on the immune system of her organ donor, doctors said on Friday, calling her a "one-in-six-billion miracle."

Demi-Lee Brennan, now 15, received a donor liver when she was 9 years old and her own liver failed.

"It's like my second chance at life," Brennan told local media, recounting how her body achieved what doctors said was the holy grail of transplant surgery. "It's kind of hard to believe."

Brennan's body changed blood group from O negative to O positive when she became ill while on drugs to avoid rejection of the organ by her body's immune system.

Her new liver's blood stem cells then invaded her body's bone marrow to take over her entire immune system, meaning the teen no longer needs anti-rejection drugs.

Doctors from Sydney's Westmead Childrens' Hospital said they had no explanation for Brennan's recovery, detailed in the latest edition of The New England Journal of Medicine.

"There was no precedent for this having happened at any other time, so we were sort of flying by the seat of our pants," Michael Stormon, a pediatric hepatologist, told local radio.

Stuart Dorney, the hospital's former transplant unit head, said Brennan's treatment could lead to breakthroughs in organ transplant treatment, because normally the immune system of recipients attacked the transplanted tissue.

"We now need to go back over everything that happened to Demi-Lee and see why, and if it can be replicated," said Dorney.

"We think because we used a young person's liver and Demi-Lee had low white blood cells, that could have been a reason," he told the Daily Telegraph newspaper.

Rejection is normally treated with a combination of drugs, although chronic rejection is irreversible.

Only seven-in-10 transplant operations in Australia are successful after a five-year period due to rejection complications.

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Monday, December 10, 2007

Pork workers suffer neurological symptoms from inhaled misty pig brains

From Wired News:


Minn. Slaughterhouse Workers Fall Ill


ST. PAUL, Minn. (AP) -- On the slaughterhouse floor at Quality Pork Processors Inc. is an area known as the "head table," but not because it is the place of honor. It is where workers cut up pigs' heads and then shoot compressed air into the skulls until the brains come spilling out.

But now the grisly practice has come under suspicion from health authorities.

Over eight months from last December through July, 11 workers at the plant in Austin, Minn. - all of them employed at the head table - developed numbness, tingling or other neurological symptoms, and some scientists suspect inhaled airborne brain matter may have somehow triggered the illnesses.

The use of compressed air to remove pig brains was suspended at Quality Pork earlier this week while authorities try to get to the bottom of the mystery.

"I'm still in shock, I guess," said 37-year-old Susan Kruse, who worked at the plant for 15 years until she got too weak to do her job last February. "But it was very surprising to hear that there was that many other people that have gotten this."

Five of the workers - including Kruse, who has been told she may never work again - have been diagnosed with chronic inflammatory demyelinating polyneuropathy, or CIDP, a rare immune disorder that attacks the nerves and produces tingling, numbness and weakness in the arms and legs, sometimes causing lasting damage.

New cases of CIDP occur at the rate of one or two per 100,000 people each year, according to Dr. P. James B. Dyck of the Mayo Clinic.

State health officials said there is no evidence the public is at risk - either from those afflicted or from any food leaving the plant, which supplies Hormel Foods Inc.

The working theory from two Mayo Clinic neurologists treating the workers: Exposure to pig brain tissue scattered by the compressed air triggered the illnesses.

"As we've investigated these patients, we have information that suggests very strongly that the immune system is activated very strongly in a very compelling way," said Dr. Daniel Lachance.

Compressed air could turn some brain matter into a mist that could be inhaled by workers, said Mike Doyle, a microbiologist who heads the University of Georgia's Center for Food Safety. Or the workers may have come into contact with something dangerous and then touched their noses or mouths, he said.

Scientists have yet to figure out if there is something in the brain matter that could be causing the symptoms.

"The hard part will be identifying the causative agent and associating that with the animal, showing that the animal carries it," Doyle said.

Minnesota Health Department spokesman Doug Schultz said the agency is looking into the theory but has not ruled out other causes. Kruse said the company has harvested pork brains on and off for years, depending on demand, but it's not known why workers began getting sick recently.

Quality Pork has not said what it does with the pork brains. Sold fresh and in cans, pork brains are fried and eaten in sandwiches or gravy in some parts of the country. But it is a small market, and the American Meat Institute, which represents most of the nation's pork processors, does not even track sales.

Exactly how many of the plant's 1,300 employees worked at the head table is unclear; Quality Pork's chief executive did not return calls. Kruse said there were 11 workers at the head table on any given shift, but the lineup changed because of turnover or because people were assigned other jobs.

In a rapid-fire process that is noisy, smelly and bloody, severed pigs' heads are cut up at the head table at a rate of more than 1,100 an hour. Workers slice off the cheek and snout meat, then insert a nozzle in the head and blast air inside until the light pink mush that is the brain tissue squirts out from the base of the skull.

Kruse, whose job was to remove meat from the back of the animals' heads, said she doesn't recall any spray or mist from the de-braining. The head-table workers were protected by safety glasses, helmets, gloves and belly guards, but none wore anything over their mouths or noses, she said.

Head-table workers are now required to wear plastic face shields and protective plastic or rubber sleeves, the Health Department said.

The use of compressed air to remove hog brains is relatively uncommon, according to industry officials. That's because many plants don't even remove them. And some of the processors that do extract brains simply split the hogs' skulls open.

Some of the biggest pork processors - Tyson Foods Inc., JBS Swift & Co. and Cargill Inc. - said they don't handle brains because the market isn't big enough. No pork workers at Tyson, Cargill or JBS Swift have reported symptoms similar to those of the Quality Pork employees, the companies said.

CIDP attacks the lining around the nerves, slowing or blocking the brain's signals to the muscles. But exactly what triggers the attack is unknown.

Victims can recover fairly quickly if the illness is caught early, said Dr. Kenneth Gorson, a neurologist at St. Elizabeth's Medical Center in Boston.

In advanced cases, treatment arrests the disease but doesn't reverse its effects, he said. Treatment involves infusions of immune globulin or a plasma-exchange technique that removes antibodies from the patient's blood. Another option is a steroid called prednisone.

American Meat Institute spokeswoman Janet Riley said: "We are watching the situation very closely and we've offered any help that the state health department would need. But certainly if facts came to light that justified the change in practices, you could imagine protecting the workers is critical."

Workers are worried, said Richard Morgan, who heads the union local at Quality Pork.

"The process has stopped, where they assume it was at," he said. "It could have been from something different. Nobody knows at this time. We can talk about gray matter till we're blue in the face."

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Friday, September 28, 2007

Brain-Eating Amoeba

Brain-Eating Amoeba Kills Arizona Boy

CDC: Cases Are Spiking In 2007

POSTED: 7:44 pm PDT September 26, 2007
UPDATED: 8:59 am PDT September 28, 2007

A 14-year-old Lake Havasu boy has become the sixth victim to die nationwide this year of a microscopic organism that attacks the body through the nasal cavity, quickly eating its way to the brain.Aaron Evans died Sept. 17 of Naegleria fowleri, an organism doctors said he probably picked up a week before while swimming in the balmy shallows of Lake Havasu.According to the Centers For Disease Control, Naegleria infected 23 people from 1995 to 2004. This year health officials said they've noticed a spike in cases, with six Naegleria-related cases so far -- all of them fatal.Such attacks are extremely rare, though some health officials have put their communities on high alert, telling people to stay away from warm, standing water.

"This is definitely something we need to track," said Michael Beach, a specialist in recreational water-born illnesses for the CDC."This is a heat-loving amoeba. As water temperatures go up, it does better," Beach said. "In future decades, as temperatures rise, we'd expect to see more cases."

Organism Lives In Lake Bottoms

Though infections tend to be found in southern states, Naegleria has been found almost everywhere in lakes, hot springs, even some swimming pools. Still, the CDC knows of only several hundred cases worldwide since its discovery in Australia in the 1960s.The amoeba typically live in lake bottoms, grazing off algae and bacteria in the sediment. Beach said people become infected when they wade through shallow water and stir up the bottom. If someone allows water to shoot up the nose -- say, by doing a cannonball off a cliff -- the amoeba can latch onto the person's olfactory nerve.The amoeba destroys tissue as it makes its way up to the brain.People who are infected tend to complain of a stiff neck, headaches and fevers, Beach said. In the later stages, they'll show signs of brain damage such as hallucinations and behavioral changes.Once infected, most people have little chance of survival. Some drugs have been effective stopping the amoeba in lab experiments, but people who have been attacked rarely survive, Beach said."Usually, from initial exposure it's fatal within two weeks," Beach said.Researchers still have much to learn about Naegleria, Beach said. For example, it seems that children are more likely to get infected, and boys are infected more often than girls. Experts don't know why."Boys tend to have more boisterous activities (in water), but we're not clear," he said.


Texas, Florida Report Cases

In addition to the Arizona case, health officials reported two cases in Texas and three more in central Florida this year. In response, central Florida authorities started an amoeba telephone hot line advising people to avoid warm, standing water, or any areas with obvious algae blooms.Texas health officials also have issued news releases about the dangers of amoeba attacks and to be cautious around water. People "seem to think that everything can be made safe, including any river, any creek, but that's just not the case," said Doug McBride, a spokesman for the Texas Department of State Health Services.Lake Havasu City officials also are discussing how to deal with rare amoeba attacks in the wake of Aaron Evans' death. "Some folks think we should be putting up signs. Some people think we should close the lake," city spokesman Charlie Cassens said. City leaders haven't yet decided what to do.Beach warned that people shouldn't panic about the dangers of brain-eating amoeba. Infections are extremely rare when compared with the number of times a year people come into contact with water. And there have been occasional years during the past two decades that experts noticed a similar spike in infections.The easiest way to prevent infection, Beach said, is to simply plug your nose when swimming or diving in fresh water."You'd have to have water going way up in your nose to begin with" to be infected, he said.

Aaron's Infection Started With Headache

The Evans family lives within eyesight of Lake Havasu, a bulging strip of the Colorado River that separates Arizona from California. Temperatures hover in the triple digits all summer, and like almost everyone else, the Evans family looks to the lake to cool off.On Sept. 8, he brought Aaron, his two other children and his parents to Lake Havasu to celebrate his birthday. They ate sandwiches and spent a few hours splashing around one of the beaches."For a week, everything was fine," he said.Then Aaron got the headache that wouldn't go away. Evans took him to the hospital, and doctors thought his son was suffering from meningitis. Aaron was rushed to another hospital in Las Vegas.Evans tried to reassure his son, but he had no idea what was wrong. On Sept. 17, Aaron stopped breathing as David held him in his arms."He was brain dead," David said. Only later did doctors realize the boy had been infected with Naegleria."My kids won't ever swim on Lake Havasu again."

The CDC Fact Sheet on Naegleria

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